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Publication: Diabetes Update
The Risks of Rosiglitazone

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Diabetic Digest - Wednesday, May 23, 2007
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News, updates and help from and for the diabetic community.
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Readers:

Today's issue features an extremely important article 
about the drug rosiglitazone and the discovery that its 
use "to treat type 2 diabetes may be associated with 
increased risk of heart attack and death from 
cardiovascular causes." 

Read the article and don't skip a line. It may just save 
your life. 

Regards,
Steve

Diabetic Update Newsletter 
Send Your Comments

Visit the Diabetic Update Forum and post your comments at: 
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Statement from the American College of Cardiology, American
Diabetes Association and American Heart Association Related
to NEJM article, 'Effect of Rosiglitazone on the Risk of
Myocardial Infarction and Death from Cardiovascular Causes'

ALEXANDRIA, Va., May 21, 2007 /PRNewswire-USNewswire via
COMTEX/ -- The following is a Statement from the American
College of Cardiology, American Diabetes Association and
American Heart Association Related to NEJM article, 'Effect
of Rosiglitazone on the Risk of Myocardial Infarction and
Death from Cardiovascular Causes':

Today the New England Journal of Medicine published an 
article entitled, "Effect of Rosiglitazone on the Risk 
of Myocardial Infarction and Death from Cardiovascular 
Causes." The conclusions of this analysis of previous 
studies of rosiglitazone (brand name, Avandia) suggest 
that this oral agent used to treat type 2 diabetes may 
be associated with increased risk of heart attack and 
death from cardiovascular causes.

According to ACC, ADA and AHA, this study deserves serious 
thought and follow-up. As estimated here, the overall level 
of the risk associated with rosiglitazone appears to be 
small, but nonetheless one that must be considered care-
fully.

In the meantime, patients using this drug should talk 
to their health care provider to determine the most 
appropriate course of action. Patients should not stop 
taking any prescribed medications without first discussing 
the issue with their health care provider. Further research 
will be needed in this area to provide conclusive evidence. 

It is very important to prevent diabetes when possible and 
to effectively treat it when it is present. The treatment 
of diabetes should be a team approach, with health care 
providers and patients working together to ensure patient 
education and empowerment.

The most life-threatening consequences of diabetes are 
heart disease and stroke, which strike people with diabetes 
more than twice as often as they do others. If you have 
diabetes, it is very important to control your blood 
glucose, blood pressure and cholesterol levels.

Information from the FDA for rosiglitazone can be found 
at: http://www.fda.gov/bbs/topics/NEWS/2007/NEW01636.html 

About the American College of Cardiology: 

The American College of Cardiology is leading the way to 
optimal cardiovascular care and disease prevention. The 
College is a 34,000-member nonprofit medical society and 
bestows the credential Fellow of the American College of 
Cardiology upon physicians who meet its stringent 
qualifications. The College is a leader in the formulation 
of health policy, standards and guidelines, and is a 
staunch supporter of cardiovascular research. The ACC 
provides professional education and operates national 
registries for the measurement and improvement of quality 
care. 

About the American Diabetes Association

The American Diabetes Association is the nation's premier 
voluntary health organization supporting diabetes research, 
information and advocacy. Founded in 1940, the Association's
mission is to prevent and cure diabetes and to improve the 
lives of all people affected by diabetes. The Association's 
commitment to research is reflected through its scientific 
meetings; education and provider recognition programs; and 
its Research Foundation and Nationwide Research Program, 
which fund breakthrough studies looking into the cure, 
prevention, and treatment of diabetes and its complications.
Visit the American Diabetes Association at 
http://www.diabetes.org or call 1-800-DIABETES 
(1-800-342-2383). 

About the American Heart Association:

Founded in 1924, the American Heart Association today 
is the nation's oldest and largest voluntary health 
organization dedicated to reducing disability and death 
from diseases of the heart and stroke. These diseases, 
America's No. 1 and No. 3 killers, and all other 
cardiovascular diseases claim over 870,000 lives a year. 
In fiscal year 2005-06 the association invested over 
$543 million in research, professional and public 
education, advocacy and community service programs to 
help all Americans live longer, healthier lives. To 
learn more, call 1-800-AHA-USA1 or visit 
http://www.americanheart.org 

SOURCE American Diabetes Association

Copyright (C) 2007 PR Newswire. All Rights Reserved 

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                       Diabetic Recipe

          Grilled Salmon Steaks with Tarragon Sauce

(makes 4 servings)

4 5-ounce (150 g) fresh salmon steaks, cut 1 inch (2.5 cm) 
thick
3 tablespoons (45 ml) fresh lemon juice
Tarragon Sauce
2 shallots, minced
2 tablespoons (8 g) chopped fresh tarragon or 2 teaspoons 
(10 ml) crushed dried
1 cup (228 g) plain nonfat yogurt
1 medium plum tomato, 3 ounce (90 g), seeded and finely 
minced 
1 tablespoon (9 g) minced flat-leaf parsley

1. Start a grill or preheat broiler. Brush both sides of 
   salmon with lemon juice. Grill for 5 to 6 minutes per 
   side, turning once, until salmon flakes when prodded 
   with the tines of a fork. 

2. Meanwhile, in a bowl, combine shallots, tarragon, 
   yogurt, tomato, and parsley. Mix well.

3. When salmon steaks are done, arrange on dinner plates 
   and spoon some of the tarragon sauce alongside. 

Per serving: 240 calories (34% calories from fat), 
             31 g protein, 9 g total fat (1.4 g saturated 
             fat), 7 g carbohydrates, trace dietary fiber, 
             77 mg cholesterol, 110 mg sodium 

Diabetic exchanges: 4 lean protein, 1/2 carbohydrate 
                    (skim milk)

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Archives: DIABETIC DIGEST Archives

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End of DIABETIC DIGEST
Copyright 2007 by NextEra Media. All rights reserved.

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