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HEALTH TIPS - Friday, February 16, 2007
"News That Keeps You Healthy"
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Vasectomies may cause dementia risk
EVANSTON, Ill., -- U.S. scientists say they have deter-
mined vasectomies might place some men at risk for an
unusual form of dementia. Northwestern University re-
searchers discovered men with primary progressive aphasia
-- a neurological disease in which people have trouble
recalling and understanding words -- have a higher rate
of vasectomy than men the same age who are cognitively
normal. Psychiatry Professor Sandra Weintraub, principal
investigator in the study, began investigating a possible
link between the surgery and PPA when one of her male
patients connected the onset of his language problem at
age 43 to the period after his vasectomy. Weintraub and
colleagues surveyed 47 men with PPA and 57 men with no
cognitive impairment. Of the non-impaired men, 16 percent
had undergone a vasectomy. In contrast, 40 percent of the
men with PPA had had the surgery. "That's a huge differ-
ence," said Weintraub, director of neuropsychology in
Northwestern's Cognitive Neurology and Alzheimer s
Disease Center. "It doesn't mean having a vasectomy will
give you this disease but it may be a risk factor to
increase your chance of getting it." The study was pub-
lished in the journal Cognitive and Behavioral Neurology.
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Facial composite systems don't work
AMES, Iowa, -- U.S. scientists said the use of computer-
generated facial composites during criminal investigations
don't produce useful images of perpetrators. Gary Wells
and Lisa Hasels of Iowa State University pointed to several
studies in which individuals attempted to create composites
of celebrities. In one study, 2.8 percent of participants
correctly named a well-known celebrity's image that had
been created by other participants using the face-composite
software. In another study, participants were unable to dis-
criminate composites of classmates from composites of stu-
dents at different schools. The researchers say the poor
results represent a mismatch between how faces are remem-
bered and how composites are produced. "Numerous lines of
evidence converge on the view that faces are generally
processed, stored and retrieved at a holistic level rather
than at the level of individual facial features," they
said. Wells and Hasels detailed their study in the
February issue of the journal Current Directions in
Psychological Science.
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Technology images tumors' genetic profile
CAMBRIDGE, Mass., -- U.S. scientists have developed a
method of screening tumors for cancer-related gene ab-
normalities that might be treated with "targeted" drugs.
Researchers at the Massachusetts Institute of Technology
and Harvard University say their findings constitute an
important step toward the era of "personalized medicine,"
in which cancer therapy will be guided by the particular
set of genetic mutations within each patient's tumor.
"It's universally recognized that cancer is a disease of
the genome, of mutations within genes responsible for
cell growth and survival, and a great deal of effort has
gone into finding those mutations, to the point where
several hundred to a thousand are now known," said the
study's senior author, Dr. Levi Garraway. "The challenge
has been how to determine which of them are involved in
each of the hundreds of kinds of cancer that occur in
humans -- and to develop accurate, affordable methods of
detecting key mutations in tumor samples. This study
suggests that such a method is feasible on a large scale."
The study appears online in the journal Nature Genetics.
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