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Gizmorama - New method to curtail tumor growth found
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New method to curtail tumor growth found
A U.S. study suggests increasing a blood pressure-regulating
enzyme in mice enhances the immune system's ability to sense
tumor growth. Emory University School of Medicine researchers
engineered mice to make more angiotensin-converting enzymes in
white blood cells called macrophages. When that occurred, the
mice could more effectively limit the growth of injected tumors.
Scientists said the enzyme works by "trimming" small bits of
protein that originate from the tumors, allowing the immune
system to identify those tumors and mount a response more
efficiently. The study's senior author, Dr. Kenneth Bernstein,
said the findings suggest a strategy for amplifying immune
system function in humans. "We think we've discovered a means
of tweaking the immune response by modifying the process of
antigen presentation," Bernstein said, suggesting physicians
might be able to enhance a cancer patient's ability to resist
a tumor by removing his or her white blood cells, boosting
their production of angiotensin-converting enzyme and re-
infusing them. The study is reported online in the Journal of
Biological Chemistry.
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Surgeons use robots during heart surgery
Some U.S. surgeons say they've started using robots to assist
them in heart bypass surgery, producing smaller incisions, less
pain and fewer complications. Boston Medical Center Dr. Robert
Poston said his facility is one of only nine U.S. hospitals to
offer robot-assisted coronary artery bypass graft, or CABG,
surgery. CABG involves removing or re-directing a blood
vessel from one part of the body, placing it around an
obstructed artery, thereby restoring blood flow to the
heart. The robot-assisted procedure allows surgeons to gain
access to the heart with several small incisions, unlike
conventional bypass surgery that requires the chest to be
opened with a 6-10 inch incision. Using the small incisions
between the ribs, the robot's arms and a small camera are
placed inside the patient's chest, providing a three-dimensional,
10-times-magnified image, Poston said. The robotic instruments
mimic the movements of the surgeon's hands and wrist, providing
flexibility and precise motion control during the procedure.
In addition to smaller scars, fewer side effects and
complications, less pain and a reduced risk of infection,
Poston said there is also the benefit of a faster recovery.
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World's first lungless frog is discovered
Scientists from the National University of Singapore say
they've discovered a lungless frog in Borneo that apparently
takes in oxygen through its skin. Researchers led by David
Bickford confirmed the first case of complete lunglessness in
a frog (Barbourula kalimantanensis), as well as two new
populations of the aquatic animal. "We knew that we would have
to be very lucky just to find the frog," said Bickford. "People
have been trying for 30 years. But when we did and I was doing
the initial dissections -- right there in the field -- I have
to say that I was very skeptical at first (that the frog would,
in fact, lack lungs). It just did not seem possible.
"We were all shocked when it turned out to be true for all
the specimens we had from Kalimantan, Indonesia, "The thing
that struck me most then and now is that there are still major
firsts to be found out in the field," he added. "All you have
to do is go a little ways beyond what people have done before,
and -- voila!" The discovery of the Bornean frog is reported
in the journal Current Biology.
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