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Heart failure med good for pulmonary edema | |
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HEALTH TIPS - Thursday, February 8, 2007
"News That Keeps You Healthy"
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Some oils may cause breast growth in boys
WASHINGTON, -- U.S. National Institutes of Health scien-
tists say repeated topical use of products containing
lavender or tea tree oils can cause enlarged breasts in
boys. The study suggests the use of such oils causes
prepubertal gynecomastia, a rare condition that reverses
itself when use of the oils is discontinued. Researchers
at the National Institute of Environmental Health
Sciences confirmed in laboratory studies what a pediatric
endocrinologist at the University of Colorado suspected
after diagnosing three of his young male patients with
prepubertal gynecomastia. The researchers found an
association between the use of soaps, skin lotions, sham-
poos or styling products containing the oils and the dis-
order but say more research is needed. At this point, the
scientists said, their findings are only applicable to
young males with unexplainable enlarged breasts who are
regularly use products containing lavender or tea tree
oils. The study appears in the current issue of the New
England Journal of Medicine.
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Heart failure med good for pulmonary edema
CALGARY, Alberta, -- Canadian scientists say acetazola-
mide, a drug used to manage fluid retention in heart
failure, can also control effects of high altitude ex-
posure. Marc Poulin and colleagues at the University of
Calgary found the drug controls the effects of pulmonary
edema -- an accumulation of fluid in lung tissue that
occurs from high altitude exposure -- as well as improv-
ing brain oxygenation. The randomized, double-blind and
placebo-controlled study showed acetazolamide had complex
positive effects on ventilation, pulmonary vascular
resistance and cerebral blood flow in optimizing brain
oxygenation during simulated high-altitude tests on nine
subjects. The researchers conclude the drug could be a
valuable means of preventing or treating high-altitude
pulmonary edema. The study's results appear in February
issue of the American Journal of Respiratory and Critical
Care Medicine, published by the American Thoracic Society.
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Obesity drug helps advance cancer research
WINSTON-SALEM, N.C.,-- U.S. cancer researchers say they've
discovered that a drug used to fight obesity can prevent
tumor cell growth and promote tumor cell death. Assistant
Professor Steven Kridel and colleagues at the Wake Forest
University School of Medicine say they are the first to
report a tubular network within cells, known as the endo-
plasmic reticulum, or ER, is regulated by an enzyme close-
ly linked with tumor growth and development. The research
showed an enzyme known as fatty acid synthase is vital for
the ER to do its job. Blocking that enzyme, which makes
fat in cells, has been shown to prevent tumor cell growth
and to promote cell death. "No one had made connection
before between fatty acid synthase and the function of
the ER in tumor cells," said Kridel. "This is the first
to show that fatty acid synthesis is important in main-
taining ER function and keeping tumor cells alive." The
researchers found Orlistat, a drug approved to treat
obesity, can block the function of fatty acid synthase,
thereby preventing tumor cell growth and promoting tumor
cell death. The study appears in the current issue of
the journal Cancer Research.
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