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Study considers measles as a cancer killer. | |
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HEALTH TIPS - Wednesday, March 7, 2007
"News That Keeps You Healthy"
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Scientists study history of bird flu virus
DAVIS, Calif., -- U.S. scientists have reconstructed the
history of the avian flu virus, providing information
that might help health officials develop interventions.
University of California-Davis researchers combined genetic
and geographic data of the H5N1 avian flu virus to
reconstruct its history during the past decade. They found
multiple strains of the virus originated in the Chinese
province of Guangdong, and also identified many of the
migration routes through which the strains spread regionally
and internationally. The researchers said by knowing where
H5N1 strains develop and how they migrate, health officials
can better limit the spread of the virus. "If you can
control the virus at its source, you can control it more
efficiently," said Professor Walter Fitch, a co-author
of the study. "With a road map of where the strain has
migrated, you're more likely to isolate the strain that
you should be using to make the vaccine." The study, which
also involved researchers Robert Wallace, Hoang-Minh Ho-Dac
and Richard Lathrop, appears in the online early edition of
the Proceedings of the National Academy of Sciences.
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Prescription-painkiller abuse on the rise
BETHESDA, Md., -- Teenagers and young adults are abusing pre-
scription drugs in staggering numbers, and the crippling
effects of this addiction must be addressed head-on, experts
said. "(We must) maximize the treating of severe pain and
minimize the risk of overdose," Nora Volkow, director of the
National Institute on Drug Abuse, told a conference on pain,
opioids and addiction at NIH headquarters in Bethesda, Md.
The conference focused on opioids, the most powerful kind of
treatment prescribed to treat nearly every type of pain.
Examples of opioids include morphine, codeine, oxycodone
(OxyContin) and hydrocodone (Vicodin). Though opioids are
effective when properly taken, the abuse of opioids and even
extended treatment with them can result in intoxication and
addictions. The dangers increase when people take opioids
in combination with over-the-counter medications such as
allergy and cold medication, as well as drugs and alcohol.
Such hazardous combinations can cause respiratory depression
and, in some cases, lead to death. Approximately 48 million
people 12 and older have used prescription drugs for non-
medical reasons, according to the NIDA, and researchers
are still trying to figure out why. For one thing, the in-
creasingly easy access to prescription medications may be
one of the reasons for the escalation of prescription-drug
use in youth. The number of drug overdoses leading to death
has doubled between 1999 and 2004 in people 15 to 24,
according to the Centers for Disease Control and Prevention.
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Study considers measles as a cancer killer
ROCHESTER, Minn., -- U.S. researchers are testing an
engineered measles virus against multiple myeloma, an
incurable cancer of the bone marrow. The start of the Mayo
Clinic's Phase 1 clinical trial marks the third of a series
of molecular medicine studies in patients testing the
potential of measles to kill cancer. The Mayo Clinic Cancer
Center is the only institution in the world currently
pursuing using engineered measles viruses for cancer treat-
ment. The therapies now being tested involve several tumor
types, including glioblastoma multiforme (a brain tumor),
recurrent ovarian cancer and now multiple myeloma. Dr.
Angela Dispenzieri, the lead researcher, said the current
study differs from two other open trials in that researchers
are administering the measles virus strain intravenously,
rather than directly to the tumor site. The researchers are
also looking at ways to use the measles virus to combat other
tumors, including those involved in breast, pancreatic and
liver cancer.
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