Publication: Health Tips
Protein saves cells, but may cause cancer | |
Subscribe FREE to Health Tips by clicking here.
HEALTH TIPS - Tuesday, Aprl 10, 2007
"News That Keeps You Healthy"
------------------------------------------------------------
Health Tips and Info From EVTV1.com Health Related Videos
------------------------------------------------------------
Protein saves cells, but may cause cancer
COLUMBUS, Ohio, -- U.S. scientists have discovered how an
unusual protein helps a cell avoid damage when making new
DNA, thereby averting the cell's self-destruction. But the
Ohio State University researchers said they also discovered
the protein -- an enzyme called Dpo4 -- often makes errors
when copying the genomic DNA sequence that later might cause
the cell to become cancerous. "Unrepaired DNA damage pres-
ents a big roadblock for the DNA replication machinery,
which cannot go around it," said Zucai Suo, an OSU assistant
professor of biochemistry, noting such damage triggers cell
death because the DNA is not replicated. Dpo4 is one of a
family of enzymes called Y-family DNA polymerases that were
discovered about 10 years ago and are only now becoming
understood. "These enzymes provide a survival mechanism for
cells," added the study's first author, graduate student
Kevin Fiala. "They allow DNA replication to continue, so the
cell doesn't die. But they don't repair the DNA damage that
exists." The findings are described in two back-to-back
papers in the current issue of The Journal of Biological
Chemistry.
------------------------------------------------------------
Lavender Breeze Aromatherapy Kit
Just $1.49 for one (1) kit... or $1.98 for two (2) kits!
This is one of those items that is so cool and everyone
loves... and with today's hectic and stressful schedules,
it's what everyone needs! With the Lavender Breeze
Aromatherapy Kit you get:
- 1 Incense Holder
- 3 Tranquility Incense Sticks
- 3 Forest Mist Incense Sticks
- 3 Sea Scape Incense Sticks
All packaged in a Compact Disk Case for as low as 99 cents
for a complete kit. It makes a wonderful gift for anyone...
even yourself. Get more details or order by visiting:
Lavender Breeze Aromatherapy Kit
------------------------------------------------------------
Drug-resistant bacteria can be controlled
BOSTON, -- U.S. medical scientists have discovered a tech-
nique that might allow them to control drug-resistant
bacteria. The Harvard Medical School researchers discovered
certain combinations of antibiotics favor the growth of non-
resistant strains at the expense of resistant ones. That
finding might help combat the spread of such microbes, as
well as shed light on microbial ecology and evolution. Roy
Kishony, an assistant professor of systems biology, and
colleagues discovered that antagonistic drug combinations,
in which the drugs' cumulative effects are less than when
they are given separately, show such properties. At sub-
lethal concentrations a mixture of doxycycline and ciprof-
loxacin preferentially selects for wild-type Escherichia
coli bacteria over that of a doxycyline-resistant strain
in a laboratory culture. The finding, said Kishony, is
surprising and counter-intuitive, since the use of anti-
biotic drugs is responsible for the generation and selection
of resistant bacterial pathogen strains. But the study
showed that with the right combinations and concentrations,
non-resistant bacterial strains can be selected. The res-
earch is detailed in this week's issue of the journal
Nature.
------------------------------------------------------------
*-------> Keychain Laser Pointer <-------
This handy laser pointer projects a beam of light over
1000 feet and comes with 5 interchangeable image heads.
This is perfect for teachers, students, tour guides, and
for presentations. Dogs and cats love this laser pointer
too, they will chase the laser beam around for hours.
Get this handy laser pointer for $1.99... Order today by
visiting:
Keychain Laser Pointer
------------------------------------------------------------
Myeloma trial results: a major success
ROCHESTER, Minn., -- The results of a multiple myeloma U.S.
clinical trial are being called a major advance in the
treatment of that disease. Scientists said the study
compared combination treatment of oral medications
lenalidomide and either high- or low-dose dexamethasone in
445 patients with newly-diagnosed myeloma -- a cancer of the
white blood cells found in bone marrow. Lenalidomide plus
high-dose dexamethasone had a one-year patient survival rate
of 86 percent. The comparative therapy using low-dose dexam-
ethasone showed a significantly higher 96.5 percent overall
patient survival rate at one year, with much less toxicity.
"In my opinion, this is the best one-year survival data that
I've seen in a large phase 3 study in myeloma," said Dr.
Vincent Rajkumar, a Mayo Clinic hematologist and primary
investigator of the study. The research was coordinated by
the Eastern Cooperative Oncology Group -- a network of
researchers at public and private institutions across the
nation. Rajkumar said all patients on the high-dose dexam-
ethasone arm of the clinical trial will be moved to the
low-dose arm. A successor study using lenalidomide plus
high-dose dexamethasone was closed early as a result of the
findings.
------------------------------------------------------------
Questions? Comments? email us: mailto: Email Health Tips
************************************************************
To get more FUN & AMUSEMENT by Email: F-R-E-E Newsletters
To see more issues like this please visit:
Health Tips Archives
Visit My Forum
____________________________________________________________
END OF HEALTH TIPS
Copyright 2007 by NextEra Media. All rights reserved.
Copyright 2007 by UPI. All rights reserved.
 E-Mail this issue
Subscribe FREE to Health Tips by clicking here.
|