Publication: Diabetes Update
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Diabetic Digest - Wednesday, August 1, 2007
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News, updates and help from and for the diabetic community.
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Readers:
It may be extremely hot outdoors, but I still need to get
some exercise. I usually take a long walk or play basket-
ball in my yard, but it has just been too hot.
I've taken to running up and down the stairs with wrist
and ankle weights on. I remember doing this when I was
younger. Before I had the weights, I held large soup cans
in my hands as I traveled up and down those stairs. It
worked great. I never got dehydrated like I would if I had
done this outside. It was a great way to get some exercise
without having to spend a ton of money of face the
unbelievable heat.
Even if the weather isn't cooperating that doesn't mean
you can stop getting a healthy dose of exercise. And if
you would rather face the heat make sure that you put on
plenty of sun-block and keep yourself hydrated. Dehydration
occurs quicker than we realize. Just keep abreast on the
quantity and frequency of hydrating yourself. You'll be
glad you did.
Regards,
Steve
Diabetic Update Newsletter
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Avandia Should Remain, Advisers Say
WASHINGTON - The widely used diabetes drug Avandia should
remain on the market, government health advisers recommend-
ed Monday, saying evidence of an increased risk of heart
attack doesn't merit removal.
The nonbinding recommendation to the Food and Drug
Administration came on a majority vote by the panel. The
tally wasn't immediately available.
"We're being asked today to take a very draconian action
based on studies that have very significant weaknesses and
are inadequate for us to make that kind of decision," said
Rebecca Killion, a Bowie, Md., diabetic and the panel's
patient representative.
However, in an earlier 20-3 vote, the panelists said that
available data show the drug does increase heart risks.
Panelists said the drug's warning label should be updated
and there should be additional study.
Earlier, FDA scientist Dr. David Graham told the joint
panel of experts that the drug's heart risks, combined with
its lack of unique short-term benefits in helping diabetics
control blood sugar, meant continued sales were not
justified.
The manufacturer, GlaxoSmithKline PLC, argued that there
is no increased risk, citing its own analyses of studies
of Avandia, also called rosiglitazone.
"The number of myocardial infarctions is small, the data
are inconsistent and there is no overall evidence
rosiglitazone is different from any other oral antidiabetes
agents," said Dr. Ronald Krall, the company's senior vice
president and chief medical officer.
The FDA convened the experts to consider whether Avandia
should be restricted to use in select patients and branded
with prominent warnings or removed altogether from sale.
Previously, the FDA had said information from dozens of
studies pointed to an increased risk of heart attack.
The FDA isn't required to follow the advice of its advisory
committees but usually does.
About 1 million Americans with Type 2 diabetes use Avandia
to control blood sugar by increasing the body's sensitivity
to insulin. That sort of treatment has long been presumed
to lessen the heart risks already associated with the
disease, which is linked to obesity. News that Avandia
might actually increase those risks would represent a
"serious limitation" of the drug's benefit, according to
the FDA.
Copyright 2007 The Associated Press. All rights reserved.
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Dietary Carbs Linked to Vision Loss
NEW YORK (Reuters Health) - The carbohydrates present
in a diet can influence the risk of age-related macular
degeneration (AMD), the most common cause of vision loss
in older adults, according to a report in the American
Journal of Clinical Nutrition.
"AMD appears to share several carbohydrate-related
mechanisms and risk factors with diabetes-related diseases,
including (eye) and cardiovascular disease," write Dr.
Allen Taylor, of Tufts University, Boston, and colleagues.
"However, to date, only one small study has addressed this
issue."
To investigate further, the researchers conducted a study
of 4,099 participants, aged 55 to 80 years, in the Age-
Related Eye Disease Study.
The team classified a total of 8,125 eyes into one of five
AMD groups based on the severity of the disease and other
factors.
Regular consumption of a diet with a high-glycemic index
- a diet containing carbs that quickly raise blood sugar
levels -- significantly increased the risk of AMD relative
to regular consumption of a diet with a low-glycemic index.
The researchers calculate that 20 percent of AMD cases
could have been prevented if subjects had consumed diets
with a low-glycemic index.
SOURCE: American Journal of Clinical Nutrition, July 2007.
Copyright 2007 Reuters Limited. All rights reserved.
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Diabetic Recipe
Linguine with Portobello Mushrooms and Broccoli
(makes 4 servings)
1/2 pound (225 g) dried linguine
1 tablespoon (15 ml) olive oil
3 garlic cloves, minced
3/4 pound (340 g) broccoli florets, cut into bite-sized
pieces
2 portobello mushrooms, 3/4 pound (340 g), cut in half and
sliced thin
3 tablespoons (45 ml) dry white or red wine (you may
substitute water or low-sodium canned beef broth)
2 14 1/2-ounce (822 g) no salt added canned chopped tomatoes
1/4 teaspoon (1.25 ml) crushed red pepper flakes
1/2 teaspoon (2.5 ml) salt (optional)
1/2 cup (118 ml) packaged fresh basil leaves, roughly chopped
1/2 cup (118 ml) pasta water
1/4 cup (25 g) grated Parmesan cheese
1. Bring a large pot of lightly salted water to a boil
and cook the pasta to al dente, according to package
directions.
2. Meanwhile, heat the oil in a large nonstick skillet.
Add the garlic, broccoli, and mushrooms. Cook over high
heat, stirring for 2 minutes, until mushrooms begin to
wilt. Reduce heat to low and add the wine, tomatoes, and
crushed red pepper flakes. Cook, simmering slowly for
2 minutes, stirring twice. Add the basil and stir.
3. Drain the pasta, reserving 1/2 cup (118 ml) pasta water.
Add to the sauce, increase heat and boil for 1 minute to
reduce slightly.
4. Divide the pasta between 4 plates. Top with sauce and
sprinkle with the cheese. Serve immediately.
Per Serving: 365 calories (17% calories from fat),
16 g protein, 7 g total fat (2.0 g saturated
fat), 61 g carbohydrate, 7 g dietary fiber,
5 mg cholesterol, 169 mg sodium
Exchanges: 3 carbohydrate (3 bread/starch), 3 vegetable,
1 fat
Copyright 1997-2001 Diabetic-Lifestyle.
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Archives: DIABETIC DIGEST Archives
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End of DIABETIC DIGEST
Copyright 2007 by NextEra Media. All rights reserved.
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