Publication: Diabetes Update
Halloween Fun | |
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Diabetic Digest - Wednesday, October 24, 2007
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News, updates and help from and for the diabetic community.
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Readers:
Halloween is only a week away and for kids with diabetes
this used to mean trouble.
When I was diagnosed at the age of 9, I was devastated
when Halloween came around. It was the only time of year
that I ever ate candy (I wasn't a big candy person). I
still dressed in costume and went house to house with
my brother to get him more candy, but I got to keep
the pennies and dimes the old ladies would give us.
As I went to a neighbor's house to trick-or-treat I
discovered they had gone out and bought some sugar free
candy just for me. Diabetes was still new to my family
and I and we had no idea that sugar free candy was
available. It was the greatest feeling to be able to
enjoy Halloween and trick-or-treating like in the past.
Today, kids with diabetes can enjoy candy on Halloween
just the same. I recently went to pick myself up some
sugar free candy and I just can't believe the variety
of candy specifically for diabetics. You just have to
remember that you can only enjoy a small amount at a
time or else you'll have to spend the majority of All
Saints' Day in the bathroom. (I learned the hard way).
Halloween is just as fun as it ever was and I'm glad.
We all know what a little treat can do for your spirits.
Regards,
Steve
Diabetic Update Newsletter
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Health Videos
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Inhaled Insulin Exubera Discontinued
NEW YORK (Reuters) - Exubera, an inhaled insulin product
for diabetes, has been withdrawn from the market by Pfizer
Inc, which is taking a $2.8 billion charge to end its
involvement with the poorly selling drug, leading to a
sharp fall in third-quarter earnings, the company said
Thursday.
Deutsche Bank analyst Barbara Ryan said Pfizer's abandon-
ment of Exubera, with revenues so far this year of only
$12 million, was irrelevant from a financial perspective.
"They tested the patient (Exubera) and there was no pulse,
so it's going from zero to zero," she said.
Exubera, designed for the treatment of diabetes type
1 or 2 had, "simply not found the acceptance of doctors and
patients," Chief Executive Jeff Kindler told analysts on a
conference call.
"We will carefully evaluate what happened here," Kindler
said, referring to the unpopularity of the product. More-
over, he said Pfizer will halt further research on second-
generation forms of inhaled insulin.
Exubera, developed in partnership with Nektar Therapeutics,
was approved by U.S. regulators in January 2006 and made
history as the first form of inhaled insulin. Other
companies are trying to develop similar products.
New York-based Pfizer said it would return its worldwide
Exubera rights to Nektar, and work with doctors over the
next three months to switch Exubera patients to other
diabetes treatments.
After being launched, many investors assumed Exubera would
become a sure-fire blockbuster on the theory that diabetics
would prefer an inhaled form of insulin over traditional
injectable forms of the hormone used to control blood
sugar.
Instead, Exubera became a dud, with paltry sales. Some
analysts speculated the bulky canister device used to
administer the powdered drug was a problem for patients.
Copyright 2006 Reuters Limited. All rights reserved.
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GLOW IN THE DARK STAIR TREADS (Set of Four)
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Company Denies New Diabetes Drug Causes Pancreatitis
COPENHAGEN (Reuters) - No increased risk of acute
pancreatitis has been observed so far in clinical trials
of the diabetes type 2 drug liraglutide, which is in late-
stage clinical trials, Denmark's Novo Nordisk, the world's
biggest maker of insulin, said on Wednesday.
The U.S. Food and Drug Administration (FDA) warned doctors
and patients on Tuesday that Amylin Pharmaceuticals Inc's
and Eli Lilly and Co's diabetes drug Byetta may be linked
to acute pancreatitis in some patients.
Novo Chief Science Officer Mads Krogsgaard told Reuters
that tests on over 3,000 patients had showed no signs of
acute pancreatitis with liraglutide compared with placebo.
"Type 2 (diabetes) patients and obese people have an
increased risk of getting pancreatitis from the outset.
So in relation to the placebo group we have not seen signs
that liraglutide causes pancreatitis," he said.
Byetta and liraglutide are both members of a new class of
medications to treat type 2 diabetes.
Byetta, which is known generically as exenatide, was
launched in the United States in mid-2005 as the first
drug in its class. Its success has been due in part to the
drug's ability to help patients shed weight.
The drug is a synthetic version of a hormone in the saliva
of the Gila monster lizard. Liraglutide is a genetically
modified version of the human hormone GLP-1, which
stimulates insulin production.
Krogsgaard said it was still too early to say if the
increased risk of pancreatitis was specific to Byetta or
if the entire class of drugs would have the same side
effects.
"The Byetta effect could be specific for Byetta because
it comes from this lizard, the Gila monster, and is
different from human GLP1. Or it could be a class effect
that will be noted for all GLP1's, ours and theirs."
Krogsgaard said Novo hopes to received regulatory approval
for liraglutide in Europe and the U.S.by mid-2008.
Copyright 2006 Reuters Limited. All rights reserved.
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Diabetic Recipe
Witch's Brew
(makes 16 servings)
dry ice
2 .32-ounce (9 g) sugar-free grape or black cherry drink mix
cold water
1 46-ounce (1.4 l) can unsweetened pineapple juice, chilled
1 quart (1 liter) sugar-free lime-flavored carbonated
beverage or sugar-free ginger ale, chilled
1. Place a punch bowl into a larger bowl so that you have
a gap of at least 3 inches between the two bowls. Fill
the gap with small pieces of dry ice.
2. Reconstitute drink mix with cold water according to
package directions, stirring until dissolved. Pour
into a punch bowl and stir in cold pineapple juice.
3. Slowly add carbonated beverage and serve.
Per 1-cup serving: 51 calories (0% calories from fat),
trace protein, 0 total fat (0 saturated
fat), 11 g carbohydrate, 0 dietary
fiber, 0 cholesterol, 3 mg sodium
Diabetic exchanges: 1 carbohydrate (fruit)
Copyright 1997-2001 Diabetic-Lifestyle.
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Copyright 2007 by NextEra Media. All rights reserved.
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