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TODAY'S CONSUMER - Friday, October 13, 2006
"News You Can Use"
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Technique boosts protein size for analysis
ITHACA, N.Y., -- U.S. scientists have increased by four-
fold the size of proteins that can be analyzed to those
containing more than 2,000 amino acids. Called a "top-
down" approach, the extended technique developed at
Cornell University uses a mass spectrometer, which
measures the masses of ions or charged particles. Re-
searchers break the protein into pieces and weigh both
the masses of the whole protein and of the individual
pieces. By matching the weight of the whole protein and
its pieces with those of known protein sequences in a
database, they can identify the protein. Any differences
in mass with known proteins can help researchers also
find where and how proteins have been modified in cells.
"When you isolate a protein from a mixture, your first
problem is to know which one it is," said Fred McLafferty,
professor emeritus of chemistry and chemical biology and
senior author of the paper. "Mass spectrometry character-
izes a protein by measuring the masses produced from it."
McLafferty says the new technique provides a far more
efficient way to break down proteins inside the mass
spectrometer. The study appears in the Oct. 6 issue of
the journal Science.
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Bubble machine produces a surprise
CHICAGO, - U.S. physicists have discovered a new class of
behavior in air bubbles rising from an underwater nozzle.
The University of Chicago scientists say they found the
bubbles surprisingly tear apart in sharp jerks instead of
pinching off at a point. That, the scientist said, is help-
ing them understand the mathematical explosions they en-
counter in the equations that govern the physics of fluids.
"These are the equations of our lives," said Wendy Zhang,
assistant professor of physics, noting the equations
govern everything from the bubbles of carbonated beverages
to the venting of gas from deep oceanic fissures. They
even apply to such large-scale processes such as exploding
stars, she said. Chicago graduate student Nathan Keim and
his co-authors Zhang, Sidney Nagel and Peder Moller,
documented their discovery using high-speed digital photo-
graphy. Keim's experiment built on previous work that
Zhang, Nagel and others published in the journal Science
in 2003. Until then, scientists believed all fluids broke
apart in much the same way. They believed the cross-
section of the pinching neck of any drop or bubble would
become circular until it broke, regardless of its initial
conditions The research appears in the journal Physical
Review Letters.
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Too many U.S. kids lead stressful lives
PHILADELPHIA, -- The United States has strayed so far from
the Victorian ideal of childhood that pediatricians should
include "stress checks" in child exams, a report says. A
new report by the Illinois-based American Academy of
Pediatrics claims that overbooking of enrichment activities
is impacting children's mental as well as physical health,
USA Today reported. Lead author of the academy report, Dr.
Kenneth Ginsburg of Philadelphia, says some U.S. children
have no time for imaginative free play and are taken from
one adult-organized activity to another. "A lot of pedia-
tricians are seeing stress in children with this kind of
schedule," Ginsburg told USA Today. "It's not true for all
kids, but it is a serious problem." The report urges par-
ents to tailor activities to their child's temperament
rather than trying to keep up with the Joneses. Psycholo-
gist David Elkind, whose book "The Hurried Child," pro-
vided similar advice 25 years ago, applauds the new
report. "They're late," says Elkind "but better late than
never."
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Copyright 2006 by United Press International.
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