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Breast cancer research is studied | |
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HEALTH TIPS - Thursday, March 1, 2007
"News That Keeps You Healthy"
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Pigs arrive in bio-secure facility
MINNEAPOLIS, -- U.S. scientists say they've taken an impor-
tant step toward finding a cure for diabetes with the open-
ing of a bio-secure facility for "medical-grade" pigs. Re-
searchers with the Spring Point Project, an organization
created to expedite the widespread availability of islet
tissue for diabetes care, say the new $6.2 million, 21,000-
square-foot Islet Resource Facility in Minneapolis will be
dedicated to finding and funding the cure for diabetes.
"Populating the Islet Resource Facility marks a major mile-
stone in our ability to offer islet transplants to all
patients with diabetes who meet medical criteria," said Dr.
Bernhard Hering, scientific director of the Diabetes
Institute for Immunology & Transplantation at the
University of Minnesota, which may run pre-clinical and
clinical trials with Spring Point Project. "Human islet
cell transplants have reversed diabetes in 90 percent of
our recipients," said Hering. "However, the shortage of
human donor organs greatly limits the applicability of
islet transplants. Pig islets will solve this demand issue
and are at the forefront of a far-reaching cure for
patients with diabetes." Pancreatic islet cells from the
approximately 100 pathogen-free pigs at the facility will
be used for transplantation into diabetes patients in
clinical trials.
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Safety of prostate cancer therapy pondered
BOSTON, -- U.S. scientists are questioning the safety of
androgen deprivation therapy for prostate cancer, saying
it might increase the risk of heart disease. The study by
researchers at the Dana-Farber Cancer Institute, Brigham
and Women's Hospital and other institutions say the ther-
apy might increase the risk of death from heart disease
in patients over age 65. Although the findings need to be
confirmed in clinical trials, the researchers say oncolo-
gists should weigh the benefits of androgen deprivation
therapy against the risk of heart problems in older pros-
tate cancer patients. "Androgen deprivation therapy is
associated with elevated body mass index, increased body
fat deposits and diabetes, all of which raise the risk of
death from heart disease," said the study's lead author,
Dr. Henry Tsai. The researchers presented their study dur-
ing the weekend at the Prostate Cancer Symposium in
Orlando, Fla., sponsored by the American Society of
Clinical Oncology, the American Society for Therapeutic
Radiology and Oncology and the Society of Urologic
Oncology.
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Breast cancer research is studied
CHAPEL HILL, N.C., -- A U.S. study suggests industry-fund-
ed breast cancer therapy research is more likely to report
positive results than non-pharmaceutical funded studies.
In addition, researchers from the University of North
Carolina at Chapel Hill and the Dana Farber Cancer Insti-
tute found significant differences in the design and nature
of clinical trials supported by the pharmaceutical industry,
as compared with trials without industry involvement. "Our
study shines a flashlight on the issue of the rising role
and potential impact of the pharmaceutical industry on
breast cancer research and highlights important questions
that need to be addressed through further research," said
Dr. Jeffrey Peppercorn, assistant professor of medicine in
University of North Carolina's school of medicine. "The
significance of our study is not to say that the drug
industry does anything wrong ... but if more and more
research is funded by drug companies, then the limited
amount of funding coming from other sources may need to
be directed to address other questions." The study is
available online at the Web site of Cancer, the journal
of the American Cancer Society.
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